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183. Faulkner LC: Pet population problem. Calif Vet 1973; 27(6):19. Feddersen-Petersen D: Social behavior of wolves and dogs. Vet Q 1994; 16(51):515. Feinberg M: Clomipramine for obsessive-compulsive disorder. Am Fam Physician 1991; 43(5):1735. Feldman S: Psychotropic herbal medications: Potential for use in companion animals. ACVB Annual Symp Anim ­Behav Res 2002 Meeting Proc, 2002:77. Fiennes R, Fiennes A: The Natural History of the Dog. ­London: Weidenfeld and Nicolson, 1968. Flament MF, Rapoport JL, Berg CJ, et al: Clomipramine treatment of childhood obsessive-compulsive disorder: A double-blind controlled study.

Fortunately, there have been a number of advances in neuropharmacology, and several more are currently being worked on (Box 1-3). Today euthanasia can be a last resort, not a first one. 26 C h a p t e r 1 Introduction to Canine Behavior BOX 1-3 Classification scheme for various psychotherapeutic drugs Antianxiety drugs Antidepressant drugs Sedative-automatic Antipsychotics Acetophenazine Haloperidol Trifluoperazine Azapirones Buspirone Gepirone Ipsapirone Diphenylmethane antihistamines Diphenhydramine Hydroxyzine Tricyclic antidepressants Amitriptyline Doxepin Sedative-hypnotic Barbiturates Butabarbital Phénobarbital Benzodiazepines Alprazolam Chlordiazepoxide Clonazepam Clorazepate dipotassium Diazepam Hafazepam Lorazepam Oxazepam Glycerol derivatives Meprobamate Tybamate Antipsychotic drugs Beta-blocking drugs Hypnotic drugs Narcotic antagonists Progestins Benzoquinolizine Tetrabenazine Butaclamol Butyrophenones Droperidol Haloperidol Dibenzodiazepine Clozapine Dibenzoxazepine Loxapine Diphenylbutylpiperidenes Penfluridol Pimozide Indolic derivative Molindone Phenothiazines Acepromazine Acetophenazine Acetylpromazine Butaperazine Chlorpromazine Propranolol Antihistamines Chlorpheniramine Diphenhydramine Methpyriline Barbiturates Pentobarbital Secobarbital sodium Benzodiazepines Flurazepam Nitrazepam Temazepam Triazolam Glutarimides Glutethimide Methyprylon Halogenated hydrocarbons Chloral hydrate Higher alcohols Ethchlorvynol Naloxone Naltrexone Medroxyprogestrone acetate Megestrol acetate Adrenergic stimulants Salbutamol Aminoketones Bupropion Benzodiazepines Alprazolam Bicyclics Zimeldine Clomipramine Lithium Monoamine oxidase inhibitors (MAOIs) Isocarboxazid l-Deprenyl Phenelzine Tranylcypromine Nomifensine Phenylpiperazines Nefazodone Trazodone Selective serotonin reuptake inhibitors (SSRIs) Citalopram Fluoxetine Fluvoxamine Paroxetine Sertraline Sympathomimetic stimulants— amphetamines Dextroamphetamine Levoamphetamine Sympathomimetic stimulants— amphetamine surrogates Magnesium pemoline Methylphenidate Pipradrol Tetracyclics Maprotiline Tricyclics Amineptine Amitriptyline Butriptyline Clomipramine Desipramine Doxepin Imipramine Maprotiline Nortriptyline Protriptyline Trimipramine Unusual tricyclics Amoxapine Chapter 1 Introduction to Canine Behavior 27 BOX 1-3 Classification scheme for various psychotherapeutic drugs—cont’d Antipsychotic drugs—cont’d Fluphenazine Mesoridazine Perphenazine Piperacetazine Promazine Thioridazine Trifluoperazine Phenylpiperazine Oxypertine Reserpine Thioxanthenes Chlorprothixene Flupenthixol Thiothixene Hypnotic drugs—cont’d Quinazolones Methaqualone A few years ago there was a rush to try the tricyclic antidepressants and selective serotonin reuptake inhibitors.

171 Progestins The exact mechanism of the progestins is not understood, but it has been speculated that they ­mimic the action of progesterone, inhibiting the brain mechanisms responsible for male ­ behavior113 or lowering serum testosterone levels. They also have an antianxiety calming effect. For those ­ reasons they have proved most useful for controlling undesirable male sexually dimorphic behaviors and behavior problems in which stress is a factor. The down side of their use is a high incidence of serious side effects with long-term use.

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