Download Drugs and Pregnancy: A Handbook (A Hodder Arnold by Bertis Little PDF

By Bertis Little

This useful guide will support the health professional and nurse prescriber in knowing the results of drug publicity while pregnant. a variety of tables and packing containers offer details on drug classifications and regimens, in addition to highlighting hostile results and TERIS and FDA possibility scores. assets of additional details are supplied the place applicable, and full references can be found at the book's site

The booklet offers specified guidance on prescribing medications in all periods, and for a large choice of ailments and problems, while pregnant. starting with a worthwhile research of strength dangers and advantages of prescribing in being pregnant, the ebook strikes directly to contemplate the results of either medicines for pre-existing stipulations and those who increase while pregnant, together with antimicrobials, medications for heart problems, bronchial asthma and endocrine issues, antineoplastic brokers, pores and skin arrangements, epilepsy remedies and psychiatric medicines. priceless assistance on anesthetic management and using ache relieving drugs while pregnant and hard work, and valuable suggestion at the attainable side-effects linked to over the counter arrangements equivalent to chilly and 'flu treatments, antihistamines and dietary vitamins can be provided.

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Additional info for Drugs and Pregnancy: A Handbook (A Hodder Arnold Publication)

Sample text

Pyrimethamine, spiramycin, and sulfadiazine These agents are used primarily to treat toxoplasmosis. Pyrimethamine, a folic acid antagonist, is also used to treat malaria. There are no adequate scientific studies of its use during pregnancy, but Hengst (1972) reported no increase in the malformation rate in 64 newborns whose mothers had taken this drug during the first half of pregnancy. Spiramycin has been used extensively in Europe during the first trimester with no apparent adverse fetal effects.

For those individuals in the pedigree who are no longer living, whether death was due to a birth defect or to a heritable disorder should be determined. It is also important to ask whether the patient’s family or the baby’s father’s family has any member who was mentally retarded, or has a chromosomal abnormality, Down syndrome, congenital heart disease, spina bifida or another neural tube defect, or any other inherited disease. When such risk factors are discovered, it is important to explore these avenues further.

It is of utmost importance to base the risk assessment and counseling upon embryonic age, not menstrual age. If the exposure occurred during embryogenesis, then it is necessary to undertake high-resolution ultrasound in an attempt to detect damage to specific organ systems or structures that were being formed during the time of the exposure. If the ultrasound scan is normal, then it is reasonable to reassure the patient of normal fetal structure within the limits of the sensitivity and specificity of ultrasound, which range from 40 to 90 percent for gross structural abnormalities when the procedure is performed by an experienced sonographer.

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