By H. Mehmet
Cell Proliferation and Apoptosis provides a close sensible consultant to telephone proliferation and apoptosis detection tools. a unique technique combining either those parts permits very important comparisons to be made. themes lined contain all elements of tissue dealing with from assortment, garage, fixation and processing via to finding and quantifying cells in numerous levels of the mobile cycle. This publication is a vital and finished functional advisor to those vital and increasing components.
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Extra resources for Cell Proliferation and Apoptosis
There is always a fraction of the cell population of any tissue that is actively cycling—this is the proliferative or growth fraction. Likewise, there are always cells that are either resting or can no longer divide. Consequently, it is possible to define proliferative or growth fraction as the ratio of cycling to cycling plus non-cycling cells. Proliferative activity is dependent on the speed of the cycle and the proportion of cells committed to the cycle (the growth fraction). The fraction of cells that are actively proliferating can be measured in vivo and in vitro using techniques described in Chapter 2.
The time taken for one cell cycle to take place varies between different tissues and species but even rapidly dividing cells, such as those involved in epithelial layer repair, will take at least 24 hours to divide once. Although it has been known for many years that cells have the ability to grow and replicate, the actual mechanisms involved have only been discovered relatively recently and there is still a great deal to be explained. 2). There is always a fraction of the cell population of any tissue that is actively cycling—this is the proliferative or growth fraction.
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