Download An Atlas of Drosophila Genes: Sequences and Molecular by Gustavo Maroni PDF

By Gustavo Maroni

Drosophila, the typical fruit fly, is the main greatly studied of all organisms from the viewpoint of genetics and cytology. This atlas summarizes what's identified concerning the nearly a hundred Drosophila genes for which the full nucleotide series is understood. every one access contains a description of the gene's molecular association and expression, the whole nucleotide and amino acid sequences, maps of attention-grabbing buildings, highlights of practical beneficial properties and promoter regulatory areas, and chosen references to the first literature. A separate part of the atlas considers diversified features of gene association as they ensue within the Drosophila genome. themes coated comprise measurement correlations between a variety of genetic components, splicing indications, translation initiation indications, and codon bias. The paintings represents a brand new milestone in summarizing present info and making it simply available to geneticists and biologists.

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Extra info for An Atlas of Drosophila Genes: Sequences and Molecular Features

Sample text

Three major and two minor alternative poly-A sites exist, and it is probable that all possible combinations of initiation and polyadenylation sites are used. The major classes of mRNAs would range from 1,524 to 1,919 bases. 3 kb long (Fyrberg et al. 1981; Bond and Davidson 1986; Vigoreaux and Tobin 1987; Chung and Keller 1990a). Developmental Pattern The gene for the cytoplasmic actin 5C is, as would be expected, transcribed in all tissues. Its maternal mRNA is uniformly distributed in preblastoderm embryos.

England, B. , Heberlein, U. and Tjian, R. (1990). Purified Drosophila transcription factor, Adh distal factor-1 (Adf-1) binds to sites in several Drosophila promoters and activates transcription. J. Biol. Chem. 265:5086-5094. Falb, D. and Maniatis, T. (1992). A conserved regulatory unit implicated in tissue-specific gene expression in Drosophila and man. Genes Dev. 6:454-465. Grell, E. , Jacobson, K. B. and Murphy, J. B. (1965). Alcohol dehydrogenase in Drosophila: Isozymes and genetic variants.

6:2080-2088. Bond-Matthews, B. and Davidson, N. (1988). Transcription from each of the Drosophila ActSC leader exons is driven by a separate functional promoter. Gene 62:289-300. Burn, T. , Vigoreaux, J. O. and Tobin, S. L. (1989). Alternative 5C actin transcripts are localized in different patterns during Drosophila embryogenesis. Dev. Biol. 131:345-355. -T. and Keller, E. B. (1990a). Regulatory elements mediating transcription from the Drosophila melanogaster Actin 5C proximal promoter. Mol. Cell.

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